If you have an accidental exposure, fluid rehydration and potentially the administration of ondansetron is key. If you are able to tolerate fluids by mouth, small sips of fluids every few minutes can be beneficial.
It is estimated that up to 10% of FPIES reactions in adults may result in low blood pressure or shock. The term “shock” is used to refer to poor blood circulation from a variety of causes. It is not completely understood why FPIES reactions sometimes lead to low blood pressure.
The oral food challenge (OFC) is performed to assess resolution of FPIES. It is important to have a shared decision-making process on proceeding with the OFC. It should be discussed with the patient that depending on the severity of the past FPIES reaction, it may be necessary to place a peripheral IV prior to starting the oral food challenge.