Food protein -Induced Enterocolitis Syndrome
What is FPIES?
Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non-IgE mediated food allergy of the gastrointestinal system.
Approximately 2-4 hours after ingesting a trigger food, patients experience profuse vomiting often leading to dehydration which may necessitate the need for emergency fluid resuscitation. 20% of patients experience hypovolemic shock.There are currently three FPIES phenotypes: acute, chronic and atypical.
The International Consensus Guidelines for the Diagnosis and Treatment of FPIES determined that first foods of introduction are the most common triggers in infants and children geographically. The most commonly reported triggers in adults are seafood and mollusks. Any food (even those thought to be hypoallergenic e.g. rice, avocado) can cause an FPIES reaction. FPIES typically starts within the first year of life, but adult onset is reported in the literature.
K52.21 is the official ICD-10 code FPIES.
US Pediatric FPIES prevalence rate
US Adult FPIES prevalence rate
Total people in US with lifetime history of FPIES
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Are You an Adult with FPIES? Researchers from the Division of Allergy at the University of Rochester, Hassenfeld Children’s Hospital at NYU Langone, Texas Children Hospital, Boston Children’s Hospital and…